Meningitis due to <i>Bacillus cereus</i>: A Case Report and Review of the Literature

Abstract

<i>Bacillus cereus</i> is infrequently associated with invasive central nervous system (CNS) disease. Infection is associated with conditions that lead to reduced host immunity and provide direct access to the CNS, such as spinal anesthesia and ventricular tubes and shunts. A case of ventriculitis secondary to <i>B cereus</i> in a patient receiving intrathecal chemotherapy is reported, along with a review of the current literature. <i>B cereus</i> can colonize medical devices, thus posing a risk for invasive disease. Despite aggressive treatment with broad-spectrum anti-infectives, the mortality of CNS invasive <i>B cereus</i> is high. Clinicians should not dismiss Gram-positive rods resembling <i>Bacillus</i> species from normally sterile sites as contaminants in critically ill patients. Appropriate antibiotic therapy should be promptly initiated to limit morbidity and mortality.