A new approach to characterize populations of <i>Schistosoma mansoni</i> from humans: development and assessment of microsatellite analysis of pooled miracidia

Abstract

Allele counts and frequency profiles from pooling provide important information about infection intensity and complexity, beyond that obtained from traditional methods. Although we are not advocating use of pooling to replace individual genotyping studies, it can potentially be useful in certain applications as a rapid and cost effective screening method for studies of S. mansoni population genetics, or as a more informative way to quantify and characterize human worm populations.