The phenomenon of apoptosis in the course of experimental trichinellosis in mice.

Abstract

Mice infected with 200 Trichinella spiralis larvae were killed at 3-69 days post infection (dpi) and the jejunum and masseter muscles were sectioned in a cryostat and examined in the Tunell method with "In situ Cell Detected Kid POD" of Boehringer-Mannheim. Data concering the exact localization and dynamic of apoptic cells in both organs are presented. The authors conclude that apoptosis plays a important role in the pathogenesis of trichinellosis.