AGAMMAGLOBULINEMIA: CLINICAL STAFF CONFERENCE AT THE NATIONAL INSTITUTES OF HEALTH

Abstract

Clinical Staff Conference1 September 1957AGAMMAGLOBULINEMIA: CLINICAL STAFF CONFERENCE AT THE NATIONAL INSTITUTES OF HEALTHCHRISTOPHER M. MARTIN, M.D., EUGENE BRONSTEIN, M.D., SHELDON DRAY, M.D.CHRISTOPHER M. MARTIN, M.D.Search for more papers by this author, EUGENE BRONSTEIN, M.D.Search for more papers by this author, SHELDON DRAY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-3-533 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCASE REPORT†A 63 year old secretary was admitted to the Clinical Center on July 20, 1954, with a chief complaint of "low resistance."Eight years previously, after having been well for 15 years, she had begun to have frequent upper respiratory infections, ulcers of the tongue and buccal mucosa, right costovertebral angle tenderness and "pleurisy." During the following year, at the age of 56, she contracted a fungus infection of the fingernails and recurrent sinusitis, tonsillitis and cervical adenitis. Blood studies by her physician revealed the hemoglobin to be 13.0 gm., and the total protein 6.5 gm. per 100...Bibliography1. GitlinHitzigJaneway DWHCA: Multiple serum protein deficiencies in congenital and acquired agammaglobulinemia, J. Clin. Investigation 35: 1199-1204, 1956. CrossrefMedlineGoogle Scholar2. GoodVarco RARL: A clinical and experimental study of agammaglobulinemia, Journal Lancet 75: 245, 1955. Google Scholar3. GoodVarcoAustZak RARLJBSJ: Transplantation studies in patients with agammaglobulinemia, 2nd Tissue Homotransplantation Conference, Ann. New York Acad. Sci. 64: 882-924, 1957. CrossrefMedlineGoogle Scholar4. JanewayAptGitlin CALD: Agammaglobulinemia, Tr. A. Am. Physicians 66: 200-202, 1953. MedlineGoogle Scholar5. Lawrence HS: The delayed type of allergic inflammatory response, Am. J. Med. 20: 428-447, 1956. CrossrefMedlineGoogle Scholar6. MartinGordonFeltsMcCullough CMRSWRNB: Studies on gamma globulin. I. Distribution and metabolism of antibodies and gamma globulin in hypogammaglobulinemic patients, J. Lab. and Clin. Med. 49: 607-616, 1957. MedlineGoogle Scholar7. MartinWaiteMcCullough CMJBNB: Antibody protein synthesis by lymph nodes homotransplanted to a hypogammaglobulinemic adult, J. Clin. Investigation 36: 405-421, 1957. CrossrefMedlineGoogle Scholar8. Tarver H: Peptide and protein synthesis. Protein turnover, in The proteins. Chemistry, biological activity, and methods, edited by Neurath, H., and Bailey, K., 1954, Academic Press, New York, pp. 1199-1296. CrossrefGoogle Scholar9. VolwilerGoldsworthyMacMartinWoodMackayFremont-Smith WPDMPPAIRK: Biosynthetic determination with radioactive sulfur of turnover rates of various plasma proteins in normal and cirrhotic man, J. Clin. Investigation 34: 1126-1146, 1955. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Bethesda, Maryland*Received for publication May 15, 1957.This is an edited transcription of a combined clinical staff conference at the Clinical Center, Bethesda, Maryland, by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Public Health Service, Department of Health, Education, and Welfare.Requests for reprints should be addressed to Joseph J. Bunim, M.D., National Institutes of Health, Bethesda 14, Maryland.†Case presentation by Dr. Martin and Dr. Bronstein. Reproduced in part by permission of the New England Journal of Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDefinition of primary immunodeficiency in 2011: a “trialogue” among friendsMolecular and Cellular Aspects of X-Linked AgammaglobulinemiaHumoral immune capacity in recurrent E. coli upper urinary tract infectionDie schweizerische Form der AgammaglobulinämiePyelonephritis und chronische interstitielle NephritisPyelonephritis im KindesalterErkrankungen der HarnwegePYELONEPHRITIS-CLINICAL AND EXPERIMENTALRenal complications of neoplastic diseaseGammaglobulin Treatment And Protection Against InfectionsIdiopathic Acquired Agammaglobulinemia Associated with ThymomaAntibodies to Enteroviruses in Hypogammaglobulinemic PatientsStudies on Acquired Hypogammaglobulinemia 1 September 1957Volume 47, Issue 3Page: 533-543KeywordsBloodHemoglobinInfectious diseasesMedical servicesMucous membranesPrevention, policy, and public healthProteinsTongueUlcersUpper respiratory tract infections ePublished: 1 December 2008 Issue Published: 1 September 1957 PDF downloadLoading ...