Full-Thickness Macular Hole after Intravitreal Injection of Ranibizumab in a Patient with Retinal Pigment Epithelium Detachment and Tear

Abstract

Intravitreal ranibizumab may create focal sites of tractional forces on the retinal surface while contraction of the choroidal neovascular membrane may also place forces on the RPE and outer retina. Both actions may have as a result contraction and tearing of the retina leading to the formation of a FTMH.