The Journal of Immunology · 1971 · 11 citations · 0 references
Life SciencesImmunologyPharmacologyCell SignalingHypersensitivityPharmacodynamicsHistamine ReleaseAllergen-induced Histamine ReleaseAntihistamine PharmacologyDrug-induced Histamine ReleaseHistamine Receptor PharmacologyHistamine ReceptorsHistamine Release InhibitionHistamine-mediated SecretionPharmacologic Histamine Release
Summary Chlorophenesin completely inhibited allergen-reagin-induced histamine and SRS-A release from monkey lung tissue. Preliminary studies suggest that chlorophenesin mediates this inhibition by activating adenylcyclase.