Electrochemical biosensors - principles and applications

TLDR

Electrochemical biosensors, first proposed and commercialized for multiple analytes, have long been studied and are commonly built on semiconductor or screen‑printed electrodes using enzymes or enzyme‑labeled antibodies as biorecognition elements. The review describes the principles and most typical applications of electrochemical biosensors. The review categorizes electrochemical biosensors into potentiometric, amperometric, and impedimetric transducers, describing representative devices and typical assays for each type.

Abstract

The first scientifically proposed as well as successfully commercialized biosensors were those based on electrochemical sensors for multiple analytes. Electrochemical biosensors have been studied for a long time. Currently, transducers based on semiconductors and screen printed electrodes represent a typical platform for the construction of biosensors. Enzymes or enzyme labeled antibodies are the most common biorecognition components of biosensors. The principles of, and the most typical applications for electrochemical biosensors are described in this review. The relevant systems are divided into three types according to the operating principle governing their method of measurement: potentiometric, amperometric and impedimetric transducers, and the representative devices are described for each group. Some of the most typical assays are also mentioned in the text.