Changes in dopamine release and dopamine D2/3 receptor levels with the development of mild obesity

Abstract

[18F]Fallypride PET studies were used to estimate regional DA D2/3 receptor levels and DA release in healthy subjects with BMI's from 19 to 35. Significant, positive correlations of BMI with DA release were seen; correlations with DA D2/3 levels were negative and of borderline significance.