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Control of mouse hepatitis virus replication in macrophages by a recessive gene on chromosome 7.
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1984
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Productive InfectionViral ReplicationRecessive GeneHepatologyMolecular VirologyViral HepatitisPathogenesisImmunologyViral PathogenesisPathologyVirologyHepatitisChromosome 7New LocusAlbino LocusAntiviral ResponseMedicineViral Genetics
We have identified and mapped a new locus that imparts resistance to productive infection of mouse hepatitis virus MHV(A59) in cultured macrophages. This locus maps 41.5 centimorgans from the albino locus on chromosome 7.