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T cell synergy in the rat: serologic characterization of T cell subsets.
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1980
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Adaptive Immune SystemT-regulatory CellImmunologyImmunologic MechanismImmunotherapyVitro MlcRadiation OncologyCell TransplantationT Cell SubsetsSerologic CharacterizationXenogeneic Monoclonal AntibodyAutoimmunityT Cell ImmunityAmplifier FunctionT Cell SynergyCell BiologyTumor MicroenvironmentT Cell BiologyCellular Immune ResponseMedicine
The W3/25+ T cell subset in rats, defined by a xenogeneic monoclonal antibody and separated by using the FACS, was demonstrated to be the proliferating cell type in the in vitro MLC and to provide an amplifier function for the W3/25- T cell subset in the generation of cytotoxic effector cells to alloantigenic targets.