Schiff base adducts of glyceraldehyde with hemoglobin. Differences in the Amadori rearrangement at the alpha-amino groups.

Abstract

The Schiff-base adducts of glyceraldehyde with the amino groups of hemoglobin A undergo Amadori rearrangement to form ketoamine adducts, a reaction analogous to the nonenzymic glycosylation of proteins (Acharya,