Comparative incidence patterns and trends of gonadal and extragonadal germ cell tumors in England, 1979 to 2003

Abstract

The age-incidence patterns observed suggested a common initiation of GCTs in embryonic/fetal life with variable rates of tumor progression as a result of subsequent events that may be site specific. The authors concluded that future genetic studies should consider GCTs from all sites to enable a better understanding of their etiology.