Concepedia

Publication | Closed Access

Nitric Oxide Synthase Is Deficient in the Aganglionic Colon of Patients With Hirschsprung's Disease

DOI

47

Citations

0

References

1994

Year

John F. Bealer, Eileen Natuzzi, C. Buscher, Alan W. Flake, N.Scott Adzick, Michael R. Harrison, Philip C. Ursell
PEDIATRICS

Abstract

We conclude that aganglionic colon is deficient in NO synthase-containing nerves. This deficiency could prevent smooth muscle relaxation in the aganglionic colon of patients with Hirschsprung's disease.