Pharmacokinetics of Mycophenolate Mofetil and Intravenous Ganciclovir Alone and in Combination in Renal Transplant Recipients

Abstract

The single-dose pharmacokinetics of mycophenolic acid and its glucuronide metabolite were unchanged by the addition of ganciclovir. Total serum clearance of ganciclovir was unchanged by the addition of mycophenolate mofetil, however, renal clearance was slightly decreased.