Dermatology Online Journal · 2006 · 13 citations · 0 references
MedicineAnatomyPediatricsCraniofacial GeneticsHuman GeneticsPediatric PathologyCongenital Craniofacial AnomaliesCongenital Hand AnomaliesCongenital Limb DeformitiesCongenital Musculoskeletal DisordersCongenital Skin DisordersCongenital Lower Extremity AnomaliesCongenital Toe AnomaliesCongenital Toe DeformitiesLimb DefectsScalp DefectsTerminal Transverse Limb DeficiencyToenail Congenital Anomalies
Adams-Oliver syndrome is a rare congenital anomaly complex characterized by aplasia cutis congenita (ACC) and terminal transverse limb defects. We present a 9-year-old girl with a large, congenital scalp defect on her vertex, without underlying bone defect. Brachydactyly and syndactylia of her toes were also evident. Her 13-year-older brother had an 8 x 5 cm scalp defect without any limb defects (isolated ACC).