PEDIATRICS · 1973 · 37 citations · 0 references
MedicinePediatricsRespiratory TherapyPediatric PulmonologyVentilationVentilator ManagementAirway ManagementContinuous Positive Airway PressureMechanical VentilationPediatric Respiratory CarePositive Airway Pressure TherapyPositive End-expiratory PressureAirway Management In InfantsAirway Management In NewbornsAirway Pressure ManagementLung-protective Ventilation In ChildrenMechanical Ventilation In ChildrenMechanical Ventilation ManagementNeonatal Mechanical VentilationPediatric Positive Airway Pressure Therapy
During the years 1969, 1970, and 1971, 120 infants with hyaline membrane disease were studied, of whom 71 were treated with artificial ventilation. Among other changes in 1971, positive end-expiratory pressure was applied during mechanical ventilation and continuous positive airway pressure maintained during the weaning period. The survival rate of the ventilated babies increased from 23% in the preceding two years to 70% in 1971. As this study is not a controlled trial, the observed increase in survival cannot be ascribed to the application of increased airway pressure alone. The data presented, though necessarily inconclusive, may be useful for continuing comparisons with other pediatric centers.