16α‐Hydroxycleroda‐3,13 (14)Z‐dien‐15,16‐olide from <i>Polyalthia longifolia</i>: a safe and orally active antileishmanial agent

Abstract

The data reveal Compound 1 is a potent and safe antileishmanial. The study further exploited the structural determinants responsible for its non-cytotoxic and potent activity, to raise the feasibility of specifically targeting the target enzyme responsible for its activity through rational drug design.