Concepedia

Midkine expression in oral squamous cell carcinoma and leukoplakia

Bruno Correia Jham, Nádia Lago Costa, Janine Mayra da Silva, Alessandra Castro de Miranda, José Carlos Oliveira, Tarcı́lia Aparecida Silva, Aline Carvalho Batista

Journal of Oral Pathology and Medicine · 2011 · 15 citations · 18 references

DOI

Abstract

OCSCC, particularly late-stage tumors, exhibits increased MK expression, which may be involved in tumor progression via upregulation of anti-apoptotic genes, as shown by the augmented bcl-2 positivity in MK-positive tumors.

References

18

Cancer Statistics, 2006

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth M. Ward et al. · CA A Cancer Journal for Clinicians · 2006 · 5.3K citations · Full text

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Cancer Statistics, 2001

Robert T. Greenlee, M. B. Hill-Harmon, Thomas S. Murray et al. · CA A Cancer Journal for Clinicians · 2001 · 3.3K citations · Full text

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cDNA cloning and sequencing of a new gene intensely expressed in early differentiation stages of embryonal carcinoma cells and in mid-gestation period of mouse embryogenesis

Kenji Kadomatsu, Mineko Tomomura, Takashi Muramatsu · Biochemical and Biophysical Research Communications · 1988 · 482 citations

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A new family of heparin-binding growth/differentiation factors: increased midkine expression in Wilms' tumor and other human carcinomas.

Jun‐ichiro Tsutsui, Kenji Kadomatsu, Shuichiro Matsubara et al. · PubMed · 1993 · 238 citations

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Purification of recombinant midkine and examination of its biological activities: Functional comparison of new heparin binding factors

Hisako Muramatsu, Takashi Muramatsu · Biochemical and Biophysical Research Communications · 1991 · 204 citations

, , +7