Distribution and clinical correlates of viral and host genotypes in <scp>C</scp>hinese patients with chronic hepatitis <scp>C</scp> virus infection

Abstract

Most HCV-infected Han Chinese patients were IL28B genotype CC (rs12979860). HCV genotypes varied by geographic region, and disease characteristics differed according to HCV genotype. Relatively frequent detection of advanced liver disease may reflect limitations on access to antiviral therapy, and suggests that greater awareness of factors that influence HCV-associated disease may help avoid clinical complications and improve patient outcomes.