Immune therapy with cultured microglia grafting into the injured spinal cord promoting the recovery of rat's hind limb motor function.

Abstract

Grafting of activated microglia into the injured spinal cord can significantly promote the hind limb motor function recovery in rats with spinal cord injury and reduce the size of liquefaction necrosis area. The extent of lower limb motor function improvement has a positive correlation with the number of aggregated microglia.