Experiments on the chemotherapy of cancer

Abstract

IN a series of recent papers Synthetic methyl salicylate had no such effect. Strong [1938, 1] showed that the effective substance was in the low-boiling fraction of the oil, and later that it was probably heptaldehyde [Strong, 1938, 2]. For this reason a number of aldehydes and ketones have been tested for their inhibitory action on the growth ofgrafted tumours in mice. The more promising compounds, citral and phloroglucinol aldehyde, have been tested on spontaneous tumours in mice.