Mechanism of action of lonidamine in the 9L brain tumor model involves inhibition of lactate efflux and intracellular acidification

High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase

Ernesto Bustamante, Peter L. Pedersen · Proceedings of the National Academy of Sciences · 1977 · 394 citations · Full text

Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP.

Komal Arora, Peter L. Pedersen · Journal of Biological Chemistry · 1988 · 319 citations · Full text

Hexokinase Bound, Mitochondrial Biology, Metabolic Remodeling +23

L-lactate transport in Ehrlich ascites-tumour cells

Terry L. Spencer, Albert L. Lehninger · Biochemical Journal · 1976 · 241 citations · Full text

Glycolysis, respiration, and anomalous gene expression in experimental hepatomas: G.H.A. Clowes memorial lecture.

Sidney Weinhouse · PubMed · 1972 · 230 citations

Anomalous Gene Expression, Cell Physiology, Hepatology +15

Lonidamine, a selective inhibitor of aerobic glycolysis of murine tumor cells.

Aristide Floridi, Marco G. Paggi, Maria Luisa Marcante et al. · PubMed · 1981 · 213 citations

Metabolic Remodeling, Redox Biology, Tumor Biology +19