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Quantitative semi-micro hemagglutination. A sensitive assay dependent upon cellular dissociation and migration in capillary tubes.
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1966
Year
EngineeringQuantitative AssayImmunologyPathologyBiomedical EngineeringSensitive AssayLaboratory HematologyBioanalysisHematologySerum AgglutininsAnalytical ChemistryClinical ChemistryLaboratory MedicineMicrofluidicsChromatographyCapillary NetworkVascular BiologyBiomedical AnalysisInexpensive ProcedureCellular DissociationQuantitative Semi-micro HemagglutinationHemostasisMedicine
Summary A relatively inexpensive procedure for the quantitative assay of serum agglutinins is proposed. It offers simplicity and convenience in operation and sensitivity and reproducibility in results. The technique is based on the migration of cells down the inclined trough of a sealed micro-hematocrit tube. This system appears to depend upon the rate of cellular detachment from a centrifuged pellet by the dissociative force of gravity.