Dexmedetomidine and ST‐91 analgesia in the formalin model is mediated by α_2A‐adrenoceptors: a mechanism of action distinct from morphine

Abstract

These findings suggest that alpha(2A)-adrenoceptors mediate dexmedetomidine and ST-91 analgesia. This effect could be through a mechanism postsynaptic to primary afferent terminals, distinct from that of morphine.