THE SERUM POLYSACCHARIDE-PROTEIN RATIO (PR) AS A MEASURE OF RHEUMATOID ARTHRITIS ACTIVITY

Abstract

Article1 October 1954THE SERUM POLYSACCHARIDE-PROTEIN RATIO (PR) AS A MEASURE OF RHEUMATOID ARTHRITIS ACTIVITYR. W. PAYNE, M.D., M. R. SHETLAR, Ph.D., JANE A. BULLOCK, M.S., D. R. PATRICK, B.S., A. A. HELLBAUM, Ph.D., M.D., W. K. ISHMAEL, M.D., F.A.C.P.R. W. PAYNE, M.D.Search for more papers by this author, M. R. SHETLAR, Ph.D.Search for more papers by this author, JANE A. BULLOCK, M.S.Search for more papers by this author, D. R. PATRICK, B.S.Search for more papers by this author, A. A. HELLBAUM, Ph.D., M.D.Search for more papers by this author, W. K. ISHMAEL, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-41-4-775 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAn elevated serum polysaccharide-protein ratio (PR) occurs in active rheumatoid arthritis and certain other collagen diseases.1 The present study is concerned with the value of this serum component in assessing the degree of rheumatoid activity.METHODSPatients were studied at the Arthritis Clinic of University Hospitals and at the Arthritis Section of the Bone and Joint Hospital in Oklahoma City. Clinical classification of the rheumatoid state was made according to the criteria of Steinbrocker.2However, as this classification does not provide a scale for measuring the degree of rheumatoid activity, the patients in this report were further classified as to...Bibliography1. ShetlarPayneBullockPatrickHellbaumIshmael MRRWJADRAAWK: Comparative studies of serum polysaccharides in rheumatoid arthritis and degenerative joint disease, J. Clin. Investigation 32: 1208-1213, 1953. CrossrefMedlineGoogle Scholar2. SteinbrockerTraegerBatterman OCHRC: Therapeutic criteria in rheumatoid arthritis, J. A. M. A. 140: 659-662, 1949. CrossrefMedlineGoogle Scholar3. ShetlarFosterEverett MRJVMR: Determination of serum polysaccharides by the tryptophane reaction, Proc. Soc. Exper. Biol. and Med. 67: 125-130, 1948. CrossrefMedlineGoogle Scholar4. Milne J: Serum protein fractionations: a comparison of sodium sulfate precipitation and electrophoresis, J. Biol. Chem. 169: 595-599, 1947. CrossrefMedlineGoogle Scholar5. WintrobeLandsberg MMJW: A standardized technique for the blood sedimentation test, Am. J. M. Sc. 189: 102-115, 1935. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Oklahoma City, Oklahoma*Received for publication February 1, 1954.From the Departments of Pharmacology, Biochemistry, and Medicine, University of Oklahoma School of Medicine, and Research Laboratory of Veterans Hospital, Oklahoma City, Oklahoma.Supported in part by funds made available to The Western Oklahoma Arthritis Association by The Oklahoma City Community Fund. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMucosaccharides and glycoproteinsCHAPTER v: STUDIES IN ANEMIA AND PLASMA PROTEIN DISTURBANCESGENERAL DISCUSSIONIndices of activity in rheumatic fever treated with corticosteroidsDer Blutspiegel verschiedener Eiweißzucker in Abhängigkeit vom Druck im kleinen Kreislauf und der O2-Sättigung des BlutesRheumatoid Arthritis and Hepatocellular InjuryRheumatoid Arthritis and Hepatocellular InjuryMucosaccharides and glycoproteinsRHEUMATISM AND ARTHRITIS: REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (TWELFTH RHEUMATISM REVIEW)* Part IICHARLEY J. SMYTH, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., WILLIAM S. CLARK, M.D., F.A.C.P., DARRELL C. CRAIN, M.D., F.A.C.P., FELIX E. DEMARTINI, M.D., IVAN F. DUFF, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P. (C), MAX M. MONTGOMERY, M.D., F.A.C.P., BERNARD M. NORCROSS, M.D., F.A.C.P., HOWARD F. POLLEY, MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P.Mucosaccharides and GlycoproteinsSeromucoid and Protein-Bound Hexoses in SerumLes Reactions Serologiques de la Polyarthrite Chronique RhumatismaleObjective evaluation of patients with rheumatic diseasesLaboratory Aids in Steroid TherapyFRACTIONATION OF THE PROTEINS OF HUMAN SYNOVIAL FLUID AND PLASMA 1 October 1954Volume 41, Issue 4Page: 775-779KeywordsArthritisBiochemistryBoneHospital medicineHospitalsPharmacologyResearch laboratoriesRheumatoid arthritis ePublished: 1 December 2008 Issue Published: 1 October 1954 PDF downloadLoading ...