Performance of the Roche cobas 4800 high‐risk human papillomavirus test in cytologic preparations of squamous cell carcinoma of the head and neck

Abstract

Concordance in HNSCC HR-HPV status between cobas and ISH/IHC was > 90%, and cobas demonstrated a sensitivity of 100% and a specificity of 86%, broadening options for HR-HPV testing of fine-needle aspiration samples. Advantages for this system include subtyping of HR-HPV and the ability to discern HR-HPV status earlier in a patient's treatment course.