Storage media enhance osteoclastogenic potential of human periodontal ligament cells via RANKL‐independent signaling

Abstract

PDL cells kept in the three storage media led to TRAP+ multinucleated, osteoclast-like cells formation via RANKL-independent signaling. The ability to induce osteoclastogenesis may be considered as one of the factors to evaluate the ability of storage medium to maintain PDL viability after tooth avulsion.