The Antibacterial Efficacy Of Gold Nanoparticles Derived From Gomphrena Celosioides And Prunus Amygdalus (Almond) Leaves On Selected Bacterial Pathogens

Abstract

Gold nanoparticles (AuNPs) have gained increasing<br> interest in recent times. This is greatly due to their special features,<br> which include unusual optical and electronic properties, high stability<br> and biological compatibility, controllable morphology and size<br> dispersion, and easy surface functionalization. In typical synthesis,<br> AuNPs were produced by reduction of gold salt AuCl4 in an<br> appropriate solvent. A stabilizing agent was added to prevent the<br> particles from aggregating. The antibacterial activity of different<br> sizes of gold nanoparticles was investigated against Staphylococcus<br> aureus, Salmonella typhi and Pseudomonas pneumonia using the disk<br> diffusion method in a Müeller–Hinton Agar. The Au-NPs were<br> effective against all bacteria tested. That the Au-NPs were<br> successfully synthesized in suspension and were used to study the<br> antibacterial activity of the two medicinal plants against some<br> bacterial pathogens suggests that Au-NPs can be employed as an<br> effective bacteria inhibitor and may be an effective tool in medical<br> field. The study clearly showed that the Au-NPs exhibiting inhibition<br> towards the tested pathogenic bacteria in vitro could have the same<br> effects in vivo and thus may be useful in the medical field if well<br> researched into.