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Characterization of Corn1 mice: Alteration of epithelial and stromal cell gene expression.

15

Citations

0

References

2001

Year

I‐Jong Wang, Candace W.-C. Kao, Chia‐Yang Liu, Shizuya Saika, Patsy M. Nishina, J P Sundberg, Robin S Smith, Winston W.‐Y. Kao
PubMed

Abstract

Hyperproliferative epithelial cells of corn1/corn1 mice have increased levels of expression of keratin 14 and involucrin, but do not exhibit the phenotypical characteristics of cornification. These observations indicate that factors associated with the phenotypes of corn1/corn1 mice do not alter the cornea-type epithelial differentiation of keratin 12 expression, but cause aberrant expression of lumican by corneal epithelial cells.