Concepedia

Production and characterization of monoclonal antibodies against the Epstein-Barr virus membrane antigen

Bruce C. Strnad, Timothy Schuster, R Klein, Ralph F. Hopkins, Tracy J. Witmer, Russell H. Neubauer, Harvey Rabin

Journal of Virology · 1982 · 102 citations · 17 references

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Abstract

Five murine hybridoma lines that produce monoclonal antibodies against Epstein-Barr virus membrane antigen (MA) were established. Immunoprecipitation experiments demonstrated that three of the antibodies precipitated both the 236,000 (236K) MA and the 212K MA. The other two antibodies precipitated the 86K MA. Antibodies against the 236K-212K MA and the 86K MA mediated complement-dependent cytolysis of Epstein-Barr-virus-infected cells. The antibodies against the 86K MA neutralized both the B95-8 and P3HR-1 viruses.

References

17

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

Pamela J. Fraker, John C. Speck · Biochemical and Biophysical Research Communications · 1978 · 4.6K citations

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Surface-specific iodination of membrane proteins of viruses and eucaryotic cells using 1,3,4,6-tetrachloro-3α,6α-diphenylglycoluril

Mary Ann K. Markwell, Colin Fox · Biochemistry · 1978 · 897 citations

External Labeling of Cell Surface Galactose and Galactosamine in Glycolipid and Glycoprotein of Human Erythrocytes

Carl G. Gahmberg, Sen‐itiroh Hakomori · Journal of Biological Chemistry · 1973 · 695 citations · Full text

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Persisting oncogenic herpesvirus induced by the tumour promoter TPA

Harald zur Hausen, Frank J. O’Neill, U.K. Freese et al. · Nature · 1978 · 631 citations

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The isolation of hybrid cell lines producing monoclonal antibodies against the p15(E) protein of ecotropic murine leukemia viruses

Robert C. Nowinski, Mark E. Lostrom, Milton R. Tam et al. · Virology · 1979 · 322 citations

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