Erythropoietin administration is associated with short-term improvement in glomerular filtration rate after ischemia-reperfusion injury

Abstract

EPO attenuated the renal dysfunction as estimated as GFR. This effect was not related to changes in the hemodynamics. The immunomodulatory effects of EPO were manifested as decreased levels of TNF-α and IL-10 in renal biopsies and TNF-α levels in plasma.