Concepedia

Monitoring the AML1/ETO fusion transcript to predict outcome in childhood acute myeloid leukemia

Li Zhang, Zeng Cao, Min Ruan, Qiang Zeng, Liang Zhao, Qinghua Li, Yao Zou, Jianxiang Wang, Xiaofan Zhu

Pediatric Blood & Cancer · 2014 · 22 citations · 24 references

DOI

Abstract

Both RT-PCR and RQ-PCR can be used to detect MRD in childhood AML1/ETO AML. RQ-PCR can identify patients who are at high risk of relapse earlier than can RT-PCR.

References

24

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Minimal residual disease monitoring by quantitative RT-PCR in core binding factor AML allows risk stratification and predicts relapse: results of the United Kingdom MRC AML-15 trial

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