Heart ischaemia–reperfusion induces local up‐regulation of vasoconstrictor endothelin ET_B receptors in rat coronary arteries downstream of occlusion

Abstract

Ischaemia-reperfusion induced local up-regulation of ETB receptors in the smooth muscle cells of coronary arteries in the post-ischaemic area. In contrast, in non-ischaemic areas, ETB receptor function was unaltered.