Measuring whole‐body neutrophil redistribution using a dedicated whole‐body counter and ultra‐low doses of ¹¹¹Indium

Abstract

Assuming neutrophils are distributed only between blood, liver, spleen and bone marrow, the data suggest that marrow pools 25% and destroys 67% of circulating neutrophils, rising in COPD to 40% and 80%, respectively, possibly as a result of the effects on marrow of chronic hypoxaemia.