Discomfort assessment in peripheral angiography: Randomized clinical trial of Iodixanol 270 versus Ioversol 320 in diabetics with critical limb ischemia

Abstract

Iodixanol caused less frequent and severe discomfort, characterized as pain and heat during intra-arterial administration compared with Ioversol. The pain severity is tightly related to image and diagnosis quality with an impact on the patients for additional injections and larger CM volumes.