ALTERED IMMUNOLOGIC REACTIONS IN SARCOIDOSIS

Abstract

Article1 February 1954ALTERED IMMUNOLOGIC REACTIONS IN SARCOIDOSISMAURICE SONES, M.D., F.A.C.P., HAROLD L. ISRAEL, M.D., F.A.C.P.MAURICE SONES, M.D., F.A.C.P.Search for more papers by this author, HAROLD L. ISRAEL, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-40-2-260 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is widely accepted that in patients with sarcoidosis tuberculin sensitivity is infrequent or is of a low level and transient in nature. The mechanism responsible for the absence or loss of tuberculin sensitivity in these patients is not known. The suggestion1 that the low incidence of tuberculin reactions in sarcoidosis is merely the result of residence in areas of low tuberculosis morbidity is not valid, for it has been shown that patients with sarcoidosis fail to develop tuberculin sensitivity following repeated injections of BCG vaccine.2The diminished sensitivity to tuberculin observed in patients with sarcoidosis has been attributed to...Bibliography1. MichaelColeBeesonOlson MRMPBBJ: Sarcoidosis: preliminary report on study of 350 cases with special reference to epidemiology, Am. Rev. Tuberc. 62: 403, 1950. MedlineGoogle Scholar2. IsraelSonesSteinAronson HLMSCJD: B.C.G. vaccination in sarcoidosis, Am. Rev. Tuberc. 62: 408, 1950. MedlineGoogle Scholar3. Martenstein H: Wirkung des Serums von Sarkoid-Boeck und Lupus pernio Kranken auf Tuberkulin, Arch. f. Dermat. u. Syph. 136: 317, 1921. CrossrefGoogle Scholar4. JadassohnMartenstein WH: Uber die Abschwaechung der Tuberculin Wirkung durch menschliches Serum, Klin. 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Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication July 1, 1953.From the Woman's Medical College of Pennsylvania, and the Graduate School of Medicine and the Henry Phipps Institute of the University of Pennsylvania.These studies were supported by grants from the National Institutes of Health, Department of Health, Education and Welfare. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDisease Recurrence and Acute Cellular Rejection Episodes During the First Year After Lung Transplantation Among Patients With SarcoidosisSarcoidosis Blood Transcriptome Reflects Lung Inflammation and Overlaps with TuberculosisThe Anergic State in Sarcoidosis Is Associated with Diminished Dendritic Cell FunctionDelayed Cutaneous Hypersensitivity Tests and Lymphopenia as Activity Markers in SarcoidosisThalidomide Induces Granuloma Differentiation in Sarcoid Skin Lesions Associated with Disease ImprovementHistometric studies on cellular infiltrates of tuberculin tests in patients with sarcoidosis.Pulmonary SarcoidosisPulmonary Sarcoidosis: A Disease Characterized and Perpetuated by Activated Lung T-LymphocytesRONALD G. CRYSTAL, M.D., WILLIAM C. ROBERTS, M.D., GARY W. HUNNINGHAKE, M.D., JAMES E. GADEK, M.D., JACK D. FULMER, M.D., BRUCE R. LINE, M.D.SarcoidosisImmunologic Abnormalities in SarcoidosisRONALD P. DANIELE, M.D., JAMES H. DAUBER, M.D., MILTON D. ROSSMAN, M.D.Skin tests with tuberculin (PPD) Candida albicans and Trichophyton spp. in cryptogenic fibrosing alveolitis and asbestos related lung diseaseHerpes simplex encephalitis and sarcoidosisSarkoidoseSarcoidosis in Hypersensitivity PneumonitisCell-mediated immunity in sarcoidosis: effect of corticosteroidsLymphocyte Subpopulations in Sarcoidosis: Correlation with Disease Activity and DurationRONALD P. DANIELE, M.D., DAVID T. ROWLANDS Jr., M.D.SarcoidSARCOID LYMPHOCYTES: B- AND T-CELL QUANTITATIONANTIBODIES TO T CELLS IN SARCOIDOSISKINETICS OF MONOCYTE RECEPTOR ACTIVITY FOR IMMUNOPROTEINS IN PATIENTS WITH SARCOIDOSISLe test au DNCB dans l'exploration de l'hypersensibilité retardéeMonocyte Receptor Activity in Normal Individuals and Patients with SarcoidosisClinical immunologic responsiveness in malignant disease.I. Delayed hypersensitivity reaction and the effect of cytotoxic drugsHapten-protein conjugates as antigens for evaluation of immune competence in manSarcoidosis in childrenIMMUNOHISTOCHEMISTRY OF SARCOIDOSISCutaneous anergy without systemic diseaseStudies of Immune Mechanisms in LeprosyOccasional SurveyDelayed hypersensitivity in regional enteritis and ulcerative colitisAltered Immunologic Activity in SarcoidosisC. E. BUCKLEY III, M.D., H. NAGAYA, M.D., HEBERT O. SIEKER, M.D., F.A.C.P.Zur Immunologie der SarkoidoseErste wissenschaftliche SitzungMacrocryoglobulinemia and sarcoidosisIMMUNOLOGIC STUDIES OF THYMECTOMIZED AND NONTHYMECTOMIZED PATIENTS WITH MYASTHENIA GRAVISImmunologic Defect in Patients Recovered from SarcoidosisSuppression of Immunologic Responsiveness in UremiaW. E. C. WILSON, M.D., CHARLES H. KIRKPATRICK, M.D., DAVID W. TALMAGE, M.D.Sarcoidosis Involving the PleuraPAUL J. KOVNAT, M.D., ROBERT F. DONOHOE, M.D.Inflammation in Homograft RejectionAn Immunologic Survey of Forty-Eight Patients with Myasthenia GravisThe Biology of Tissue TransplantationLatex Fixation Tests in SarcoidosisSkin Reactions of Delayed TypeCutaneous Reactions of Household Contacts of Sarcoidosis PatientsÜber die Dissoziation der cellulären und humoralen Immunreaktionen bei Morbus Besnier-Boeck-SchaumannThe demonstration of a phenomenon in vitro applicable to the study of delayed hypersensitivityReaginic AntibodiesRETINOPATHY IN SARCOIDOSISDas Vorkommen einer dem „Rheumafaktor” analogen Serumsubstanz bei Sarkoidose (Morbus Boeck)The delayed skin test response in Hodgkin's disease and lymphosarcoma. Effect of disease activityPULMONARY ALLESCHERIASIS*RICHARD E. TRAVIS, M.D., ELIZABETH W. ULRICH, SAMUEL PHILLIPS, M.D., F.A.C.P.Gammaglobulin Treatment And Protection Against InfectionsCourse and prognosis of sarcoidosisRECENT OBSERVATIONS REGARDING THE EPIDEMIOLOGY AND PATHOGENESIS OF SARCOIDOSISPAUL W. CLOUGH, M.D.SarcoidosisPulmonary SarcoidosisTuberkulose-Antikörper bei Morbus BocckTissue culture studies of tuberculin hypersensitivity in manTHE IMMUNOLOGICAL ASPECT OF SARCOIDOSIS.Versuche einer Durchbrechung der Reaktionsschwäche für Tuberkulin beim M. BoeckProgress in sarcoidosisSkin tests in sarcoidosisTUBERCULIN IN AQUEOUS AND OILY SOLUTIONSGranulome bei MykosenMorbus BoeckDie infektiösen „spezifischen“ GranulomeMorbus BoeckHodgkin's disease and immunitySarcoidosis in ChildhoodEvidence for serologic hyper-reactivity in sarcoidosisIntracranial Boeck's Sarcoid Tumor Resembling MeningiomaThe Mumps Skin Test and Complement Fixation Test as a Diagnostic Aid in SarcoidosisTHE RIDDLE OF SARCOIDOSIS (HUTCHINSON-BOECK GRANULOMATOSIS)*WILLIAM S. MIDDLETON, M.D., M.A.C.P.SKIN SENSITIVITY IN SARCOIDOSIS 1 February 1954Volume 40, Issue 2Page: 260-268KeywordsBacille calmette guerinBacteriologyChildrenGraduate medical educationHospital medicineMorbiditySarcoidosisTuberculin ePublished: 1 December 2008 Issue Published: 1 February 1954 PDF downloadLoading ...