Publication | Closed Access
Greek Cypriot Allele and Genotype Frequencies for Amplitype® PM-DQA1 and D1S80 Loci
15
Citations
8
References
1998
Year
Genetic TestingU.s. CaucasiansGeneticsGenetic EpidemiologyHuman PolymorphismGenomicsImportant Pcr-based LociGenetic AnalysisGenotype-phenotype AssociationMolecular EcologyBiostatisticsPublic HealthHaplotype DeterminationAmplitype® Pm-dqa1Statistical GeneticsGenetic VariationGenotype FrequenciesPopulation GeneticsAllelic VariantEvolutionary BiologyGreek Cypriot AlleleMedicineGreek Cypriot Population
A sample from the Greek Cypriot population was typed at seven forensically important PCR-based loci: LDLR, GYPA, HBGG, D7S8, GC, HLA-DQA1, and D1S80. The results showed that all loci meet Hardy-Weinberg expectations and that there is no evidence for association of alleles between loci. Allelic frequency distributions at all loci, except HLA-DQA1 and two D1S80 alleles, were similar to those of U.S. Caucasians. Greek Cypriot population databases have been created and can be used for forensic analyses to estimate the frequency of a multiple locus DNA profile.
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