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Anticholinesterasic activity of Manilkara subsericea (Mart.) Dubard triterpenes

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2011

Year

Leandro Rocha, Monique Araújo de Brito, Marcelo Guerra Santos, Moacelio Verânio Silva Filho, Rodrigo Alves Soares Cruz, A. Correa, Caio P. Fernandes, Gisele da S. Botas
El Servicio de Difusión de la Creación Intelectual (National University of La Plata)

Abstract

Manilkara subsericea (Mart.) Dubard (Sapotaceae) is popularly known in Brazil as "guracica". The species from the genus Manilkara have been studied and several substances were found, including triterpenes. In the present study, we describe the anticholinesterasic activity of an extract of M. subsericea containg beta-amyrin acetate (76.3 %) and alpha-amyrin acetate (23.7 %) using a TLC bioassay.