Optics Letters · 1996 · 359 citations · 9 references
EngineeringBioengineeringBiomedical EngineeringBiomedical ImagingBiomedical OpticsOpticsFiber OpticsFiber-optic Medical DevicesOptical Coherence TomographyOptical FibersOptical ImagingOptical TomographyCatheter-based Imaging DevicesCross-sectional ImagingEndoscope DesignFiber-optic CathetersFiber-optic EndoscopesFiber-optic EndoscopyGradient-index LensesSingle-mode Optical Fibers
The study introduces a novel optical coherence tomography catheter–endoscope designed for micrometer‑scale, cross‑sectional imaging of internal organs. The device employs single‑mode fiber optics with a gradient‑index lens and microprism to emit a single spatial‑mode beam that is circumferentially scanned, enabling transverse cross‑sectional imaging. The prototype, 1.1 mm in diameter, successfully imaged in‑vitro human venous morphology.
We describe a new optical coherence tomography catheter–endoscope for micrometer-scale, cross-sectional imaging in internal organ systems. The catheter–endoscope uses single-mode fiber optics with a novel transverse scanning design. The distal end of the catheter–endoscope uses a gradient-index lens with a microprism to emit and collect a single spatial-mode optical beam with specific focusing characteristics. The beam is scanned in a circumferential pattern and can image transverse cross sections through the structure into which it is inserted. A device with a diameter as small as 1.1 mm has been achieved, and imaging of in vitro human venous morphology is demonstrated.
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