Concepedia

Synthetic studies of vitamin D analogues. VII Synthesis of 20-oxa-21-norvitamin D3 analogues.

Noboru Kubodera, Kiyoshige Ochi, Isao Matsunaga

Chemical and Pharmaceutical Bulletin · 1986 · 21 citations · 0 references

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Concepts

Life SciencesBiochemistryPharmacologyNatural Product BiosynthesisSynthetic Medicinal ChemistryVitamin BiochemistryVitamin ChemistryVitamin DVitamin D MetabolismVitamin MetabolismVitamin PhysiologyVitamin AnaloguesVitamin D AnalogsVitamin D AnaloguesVitamin D BiosynthesisVitamin D MetabolitesVitamin D Synthesis

Abstract

The synthesis of two vitamin D3 analogues, 1α, 25-dihydroxy-20-oxa-21-norvitamin D3 (2) and 1α-hydroxy-20-oxa-21-norvitamin D3(3) from dehydroepiandrosterone (4) is described.