Thalamic Deep Brain Stimulation for Orthostatic Tremor

Abstract

BACKGROUND: Orthostatic tremor is an uncommon disorder manifest by high frequency, low amplitude leg tremor upon weight bearing. Treatment with oral tremor agents is inconsistent and usually not satisfactory. METHODS: We implanted bilateral ventralis intermedius nuclei deep brain stimulators into an 82-year-old male with refractory orthostatic tremor. RESULTS: The patient had a marked subjective and objective improvement in leg and arm tremor, mainly manifested by an improved ability to stand. DISCUSSION: Bilateral thalamic deep brain stimulation may be considered in refractory cases of orthostatic tremor.