Sodium tanshinone <scp>IIA</scp> silate inhibits oxygen‐glucose deprivation/recovery‐induced cardiomyocyte apoptosis via suppression of the <scp>NF‐κB/TNF‐α</scp> pathway

Abstract

The inhibitory effects of STS on TNF-α and positive feedback signalling of the NF-κB/TNF-α pathways may play important roles in myocardial protection against ischaemia/reperfusion. These protective effects of STS are mediated by suppressing JNK activity through activation of the PI3K-Akt pathway.