The meiotic stage of nondisjunction in trisomy 21: determination by using DNA polymorphisms

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Chromatin, Dna Sequencing, Dna +15

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

Randall K. Saiki, Stephen J. Scharf, Fred Faloona et al. · Science · 1985 · 9K citations

Immunohematology, Genetic Testing, Genetics +20

Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

Louis M. Kunkel, Kirby D. Smith, Samuel H. Boyer et al. · Proceedings of the National Academy of Sciences · 1977 · 1.4K citations · Full text

Chromosome Variants, Genetic Testing, Cytogenetics +13

A genetic linkage map of the human genome

Cell · 1987 · 907 citations

Linkage Disequilibrium, Genetics, Linkage Analysis +4

Centre d'Etude du polymorphisme humain (CEPH): Collaborative genetic mapping of the human genome

J Dausset, Howard M. Cann, Daniel Cohen et al. · Genomics · 1990 · 588 citations

Genome-wide Association Study, Genetic Analysis, Medicine +8