Human papillomavirus and predictors of cervical intraepithelial neoplasia among young mothers in a prospective follow-up study

Abstract

The results indicate that combined use of cervical smear and HPV testing, with prompt referral to colposcopy, enables accurate detection of incident CIN well before progression to invasive cancer. In addition to baseline and persistent high-risk HPV, abnormal cervical smear and new sexual partner are key predictors of incident CIN.