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Alschomine and isoalschomine, new alkaloids from the leaves of Alstonia scholaris.
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1989
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BiologyNew AlkaloidsNew Indole AlkaloidBioorganic ChemistryBotanyKnown AlkaloidsNatural SciencesHerbal MedicineC-5 IsomerSecondary MetaboliteOrganic ChemistryPhytopharmacologyPhytochemicalAlstonia ScholarisPhytochemistryPharmacologyNatural Product Synthesis
A new indole alkaloid, named alschomine, was obtained from the leaves of Alstonia scholaris planted in Taipei, along with its C-5 isomer, isoalschomine, and the known alkaloids of this plant, picriinine, picralinal and nareline. The structure of alschomine was determined by X-ray analysis, supported by spectral considerations.