Severe Central Sleep Apnea Is Associated with Atrial Fibrillation in Patients with Left Ventricular Systolic Dysfunction

Abstract

AF is associated with severe CSA but not with moderate CSA in addition to age, use of digitalis, and left atrial size in patients with LV systolic dysfunction. Future studies evaluating the potential benefit of adaptive servo-ventilation therapy to prevent AF or to decrease the AF burden in heart failure patients should therefore focus on patients with severe central sleep apnea.