Correlating Partitioning and Caco-2 Cell Permeability of Structurally Diverse Small Molecular Weight Compounds

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

Ismael J. Hidalgo, Thomas J. Raub, Ronald T. Borchardt · Gastroenterology · 1989 · 2.2K citations

Life Sciences, Cell Biology, Oncology +14

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.9K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

Ismael J. Hidalgo, Thomas J. Raub, Ronald T. Borchardt · Gastroenterology · 1989 · 1.1K citations

Life Sciences, Cell Biology, Oncology +14

The Pharmacological Basis of Therapeutics, 7th ed

John L. Egle · Journal of Pharmaceutical Sciences · 1986 · 928 citations

Medicine, Pharmacology, Pharmacotherapy +10

Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability

Victor A. Levin · Journal of Medicinal Chemistry · 1980 · 814 citations

Medicine, Pharmacology, Physiology +14