Mitochondrial intermembrane inclusion bodies: The common denominator between human mitochondrial myopathies and creatine depletion, due to impairment of cellular energetics

A CASE OF SEVERE HYPERMETABOLISM OF NONTHYROID ORIGIN WITH A DEFECT IN THE MAINTENANCE OF MITOCHONDRIAL RESPIRATORY CONTROL: A CORRELATED CLINICAL, BIOCHEMICAL, AND MORPHOLOGICAL STUDY

Rolf Luft, Denis Ikkos, Genaro M. A. Palmieri et al. · Journal of Clinical Investigation · 1962 · 982 citations · Full text

Life Sciences, Endocrinology, Physiology +11

Structure of mitochondrial creatine kinase

Karin Fritz‐Wolf, Thomas Schnyder, Theo Wallimann et al. · Nature · 1996 · 297 citations

Life Sciences, Biochemistry, Biophysics +12

Muscle-type MM creatine kinase is specifically bound to sarcoplasmic reticulum and can support Ca2+ uptake and regulate local ATP/ADP ratios.

André Rossi, Hans M. Eppenberger, Pompeo Volpe et al. · Journal of Biological Chemistry · 1990 · 215 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Experimental ischemic myopathy

George Karpati, Stirling Carpenter, Calvin Melmed et al. · Journal of the Neurological Sciences · 1974 · 175 citations

Native mitochondrial creatine kinase forms octameric structures. I. Isolation of two interconvertible mitochondrial creatine kinase forms, dimeric and octameric mitochondrial creatine kinase: characterization, localization, and structure-function relationships.

Jürgen Schlegel, Beat Zurbriggen, G Wegmann et al. · Journal of Biological Chemistry · 1988 · 167 citations · Full text

Life Sciences, Biochemistry, Biology +11