Continuous epidermal growth factor delivery in corneal epithelial wound healing.

Abstract

The results indicated that continuous epidermal growth factor exposures of as few as 2 hours produced a significant increase in healing rates (P < 0.05); increasing the time of exposure further increases the rate of wound healing. Results from the concentration response experiments showed that the optimum epidermal growth factor concentration for enhancing epithelial wound healing is approximately 50 micrograms/ml.