Synthese und Chiralität des (‐)‐Cannabidiols Vorläufige Mitteilung

Abstract

Abstract N, N‐Dimethylformamide‐dineopentylacetal mediates the direct formation of (‐)‐cannabidiol from (+)‐ trans ‐ or (+)‐ cis ‐ p ‐menthadiene‐(2,8)‐ol‐(1) and olivetol. This reaction provides a simple synthetic entry into the series of optically active constituents of haschisch and defines at the same time the chirality of these compounds.